The Isle of Palms South Carolina real estate market is one of the strongest in the area, with a variety of single family homes offered for sale. This barrier island is a few blocks wide, and a few miles long. With Breach Inlet closest to the neighboring Sullivan's Island and Wild Dunes on the other end, the Isle of Palms offers a beach atmosphere on the ocean side of the island, and excellent creek and river access on the other. Combined with a laid back lifestyle, the Isle of Palms is perfect for vacationing families each year looking to have some fun in the sun. In fact, many of these visitors tend to stay because they like it so much. These are all of the single family homes for sale on the Isle of Palms, SC 29451.
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Displaying results 22-42 of 50
75 Photos
10 10th Avenue
Isle of Palms, SC 29451
Isle Of Palms
Residential
MLS# 26011313 / Active
6 br, 5 ba, 3154 Sqft
10 10th Ave, Isle of Palms - STR Opportunity meets Coastal Charm. This high-performing short-term rental boasts a proven income stream topping $200...
$3,450,000
Provided courtesy of Carroll Realty
75 Photos
304 Ocean Boulevard
Isle of Palms, SC 29451
Residential
MLS# 26011198 / Active
7 br, 7 ba, 2 Half Bath, 5402 Sqft
Welcome to 304 Ocean Boulevard--an exceptional oceanfront retreat where luxury living meets effortless coastal comfort. Situated on a rare .69-acre...
$7,900,000
Provided courtesy of The Peninsula Company, LLC
75 Photos
103 Oakview Lane
Isle of Palms, SC 29451
Forest Trail
Residential
MLS# 26010933 / Active
4 br, 4 ba, 1 Half Bath, 3000 Sqft
This is one of those homes that genuinely does not exist anywhere else on Isle of Palms.Tucked away on a quiet cul-de-sac just six blocks from the ...
$4,050,000
Provided courtesy of The Boulevard Company
73 Photos
7 2nd Avenue
Isle of Palms, SC 29451
Residential
MLS# 26010449 / Active
5 br, 3 ba, 2 Half Bath, 4784 Sqft
Enjoy your very own island oasis at 7 2nd Avenue on Isle of Palms. This charming, custom-built beach house is situated on an expansive corner lot w...
$4,195,000
Provided courtesy of William Means Real Estate, LLC
63 Photos
2201 Palm Boulevard
Isle of Palms, SC 29451
Isle Of Palms
Residential
MLS# 26010373 / Active
6 br, 4 ba, 2840 Sqft
Named the Surf Shack, you can`t ask for a better turn-key beach life than in this perfect island home across from the beach. Photos do not do it ju...
$2,750,000
Provided courtesy of Carolina One Real Estate
42 Photos
517 Carolina Boulevard
Isle of Palms, SC 29451
Residential
MLS# 26010244 / Active
5 br, 5 ba, 1 Half Bath, 3850 Sqft
Perfectly positioned just one block from the beach, this stunning 2019-built coastal retreat offers the rare combination of elevated design, expans...
$4,799,000
Provided courtesy of Smith Spencer Real Estate
66 Photos
8 29th Avenue
Isle of Palms, SC 29451
Isle Of Palms
Residential
MLS# 26009347 / Active
6 br, 6 ba, 2 Half Bath, 5023 Sqft
Built in 2023 and featuring a lot size that is uniquely generous for Isle of Palms, this exceptional 6-bedroom, 6 full bathrooms, 2 half baths, 5,0...
$4,995,000
Provided courtesy of The Cassina Group
75 Photos
2406 Palm Boulevard
Isle of Palms, SC 29451
Isle Of Palms
Residential
MLS# 26009219 / Active
4 br, 4 ba, 2 Half Bath, 5675 Sqft
From the moment you arrive, it`s clear this oceanfront property was designed for one thing: living life to its fullest. Set on an extraordinary 1.3...
$12,500,000
Reduced -$400,000
Reduced -$400,000
Provided courtesy of AgentOwned Realty Preferred Group
75 Photos
1001 Palm Boulevard
Isle of Palms, SC 29451
Residential
MLS# 26009124 / Active
5 br, 5 ba, 1 Half Bath, 4371 Sqft
Experience coastal living at its finest in this beautiful three-story, five-bedroom home along Hamlin Creek on Isle of Palms. The renovation design...
$10,200,000
Provided courtesy of ERA Wilder Realty Inc
42 Photos
4005 Cameron Boulevard
Isle of Palms, SC 29451
Residential
MLS# 26008948 / Active
4 br, 2 ba, 1604 Sqft
4005 Cameron Blvd ~ a fantastic opportunity to own a piece of paradise in one of South Carolina`s most desirable coastal communities. Timeless char...
$2,100,000
Provided courtesy of Carolina One Real Estate
62 Photos
3007 Hartnett Boulevard
Isle of Palms, SC 29451
Residential
MLS# 26007471 / Active
3 br, 2 ba, 1544 Sqft
This charming three-bedroom, two-bath home is just two blocks from the beach. It features beautiful hardwood floors throughout, an inviting screene...
$1,950,000
Provided courtesy of Palmetto Commercial Prop, LLC
11 Photos
3503 Palm Boulevard
Isle of Palms, SC 29451
Isle Of Palms
Residential
MLS# 26006873 / Active
6 br, 5 ba, 1 Half Bath, 4454 Sqft
Just one block from the beach in highly sought-after Isle of Palms, this exceptional new construction home is designed to deliver the very best of ...
$5,499,900
Provided courtesy of The Firm Real Estate Company
31 Photos
120 Palm Boulevard
Isle of Palms, SC 29451
Residential
MLS# 26006762 / Active
4 br, 4 ba, 1 Half Bath, 3993 Sqft
A rare opportunity on Isle of Palms, this newly constructed coastal residence pairs refined design with exceptional craftsmanship and sweeping view...
$5,450,000
Provided courtesy of Daniel Ravenel Sotheby's International Realty
75 Photos
112 Ocean Boulevard
Isle of Palms, SC 29451
Isle Of Palms
Residential
MLS# 26006742 / Active
7 br, 8 ba, 1 Half Bath, 6999 Sqft
Positioned along the most prestigious stretch of coastline on Isle of Palms, known as Millionaire`s Row, this extraordinary oceanfront estate repre...
$9,650,000
Provided courtesy of SERHANT
60 Photos
21 Beachside Drive
Isle of Palms, SC 29451
Beachside
Residential
MLS# 26006594 / Active
3 br, 2 ba, 1 Half Bath, 1328 Sqft
If you have been searching for the perfect beach cottage, this fully renovated home on Isle of Palms offers beach access just one block away along ...
$2,249,000
Provided courtesy of Matt O'Neill Real Estate
75 Photos
257 Forest Trail
Isle of Palms, SC 29451
Residential
MLS# 26006433 / Active
6 br, 4 ba, 1 Half Bath, 3572 Sqft
Taken down to the foundation, Completely Reimagined and Expanded, this home delivers the Quality, Design, and Efficiency of New Construction. This ...
$3,690,000
Provided courtesy of BHHS Carolina Sun Real Estate
75 Photos
3705 Palm Boulevard
Isle of Palms, SC 29451
Residential
MLS# 26006379 / Active
7 br, 5 ba, 1 Half Bath, 4700 Sqft
With ocean views, a resort-style backyard, and projected rental income of up to $500,000 annually, this beautifully renovated second-row Isle of Pa...
$4,750,000
Provided courtesy of Crown Coast Properties
34 Photos
108 Carolina Boulevard
Isle of Palms, SC 29451
Residential
MLS# 26006035 / Active
4 br, 4 ba, 2 Half Bath, 4220 Sqft
New co-ownership opportunity by Pacaso: Own one-eighth of Paradise Palms, a professionally managed, turnkey home. Located on Isle of Palms, this up...
$549,000
Provided courtesy of Pacaso Inc.
43 Photos
210 Ocean Boulevard
Isle of Palms, SC 29451
Isle Of Palms
Residential
MLS# 26004562 / Active
6 br, 5 ba, 3878 Sqft
Welcome to an a beachfront retreat where coastal elegance meets refined Lowcountry living. Set on nearly an acre of pristine IOP shoreline, this ho...
$6,900,000
Provided courtesy of Coldwell Banker Realty
34 Photos
15 42nd Avenue
Isle of Palms, SC 29451
Isle Of Palms
Residential
MLS# 26002729 / Active
6 br, 6 ba, 3787 Sqft
** Beautiful Furnished Home Priced to Sell in Quite Location on a Huge Lot ** Ideal for Large Family or Corporate Gatherings ** Steps from the Beac...
$2,750,000
Provided courtesy of EXP Realty LLC
75 Photos
3 7th Avenue
Isle of Palms, SC 29451
Isle Of Palms
Residential
MLS# 26000654 / Active
4 br, 4 ba, 1 Half Bath, 3605 Sqft
This custom-built Isle of Palms residence offers the best in coastal luxury combining elegant design, high-end craftsmanship, ocean views, and unbe...
$4,249,000
Provided courtesy of The Boulevard Company
The data relating to real estate for sale on this web site comes in part from the Broker ReciprocitySM Program of the Charleston Trident Multiple Listing Service. Real estate listings held by brokerage firms other than EXP Realty LLC are marked with the Broker ReciprocitySM logo or the Broker ReciprocitySM thumbnail logo (a little black house) and detailed information about them includes the name of the listing brokers. Last updated on 07-02-2026 6:52 PM EST .
The broker providing these data believes them to be correct, but advises interested parties to confirm them before relying on them in a purchase decision.
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