The Isle of Palms South Carolina real estate market is one of the strongest in the area, with the occasional vacant lot released into the real estate market. This barrier island is a few blocks wide, and a few miles long. With Breach Inlet closest to the neighboring Sullivan's Island and Wild Dunes on the other end, the Isle of Palms offers a beach atmosphere with a highly affluent feel, combined with a laid back lifestyle perfect for vacationing families each year.
The island was developed primarily in the early 1960’s, so there are very few vacant lots that become available. In some cases, smaller and older homes are demolished for the lot value and homes are either built or the lots are offered for sale. These are all of the vacant lots available for sale on the Isle of Palms, SC 29451.
Modify Search Criteria
Displaying results 1-6 of 6
15 Photos
1103 Palm Boulevard
Isle of Palms, SC 29451
Vacant Land
MLS# 26016067 / Active
0.16 Acres, n/a Lot(s)
Type: n/a
A rare street-to-street canvas on Isle of Palms. Situated between Palm Boulevard and Oak Harbor Boulevard, this vacant lot offers a blank slate to ...
$1,250,000
Provided courtesy of Handsome Properties, Inc.
10 Photos
37 21st Avenue
Isle of Palms, SC 29451
Vacant Land
MLS# 26014448 / Active
0.28 Acres, n/a Lot(s)
Type: n/a
Rare opportunity to build on a corner lot in the heart of Isle of Palms. Located at the corner of 21st Avenue and Waterway Boulevard, this approxim...
$1,750,000
Provided courtesy of Carolina One Real Estate
12 Photos
22 21st Avenue
Isle of Palms, SC 29451
Isle Of Palms
Vacant Land
MLS# 26004036 / Active
0.32 Acres, n/a Lot(s)
Type: n/a
A rare development opportunity awaits on Isle of Palms: a buildable lot offered with plans in hand for a 5-bedroom, 5.5-bath home. Designed with bo...
$1,825,000
Provided courtesy of The Exchange Company, LLC
1 Photos
103 Palm Boulevard UNIT A-7
Isle of Palms, SC 29451
Vacant Land
MLS# 26001889 / Active
0.00 Acres, n/a Lot(s)
Type: n/a
Enjoy 24/7 deep water access at this 35 foot boat slip on Isle of Palms at the Long Island Yacht Marina. Water and electricity available at the sli...
$255,000
Provided courtesy of iSave Realty
30 Photos
23 22nd Avenue
Isle of Palms, SC 29451
Vacant Land
MLS# 25030044 / Active
0.50 Acres, n/a Lot(s)
Type: n/a
Discover a rare opportunity to own an expansive half-acre homesite in the heart of Isle of Palms. Just a short walk from pristine beach access, thi...
$2,200,000
Provided courtesy of The Boulevard Company
15 Photos
101 Palm Boulevard UNIT B3
Isle of Palms, SC 29451
Vacant Land
MLS# 25005357 / Active
0.00 Acres, n/a Lot(s)
Type: n/a
Jet Dock designed for 18` boat up to 2,000 lbs. Perfectly situated between Sullivan`s Island and the Isle of Palms, the Two Island Marina is locate...
$99,000
Provided courtesy of Carroll Realty
The data relating to real estate for sale on this web site comes in part from the Broker ReciprocitySM Program of the Charleston Trident Multiple Listing Service. Real estate listings held by brokerage firms other than EXP Realty LLC are marked with the Broker ReciprocitySM logo or the Broker ReciprocitySM thumbnail logo (a little black house) and detailed information about them includes the name of the listing brokers. Last updated on 07-02-2026 11:00 PM EST .
The broker providing these data believes them to be correct, but advises interested parties to confirm them before relying on them in a purchase decision.
Copyright 2026 Charleston Trident Multiple Listing Service, Inc. All rights reserved.