The Isle of Palms South Carolina real estate market is one of the strongest in the area, with a variety of single family homes offered for sale. This barrier island is a few blocks wide, and a few miles long. With Breach Inlet closest to the neighboring Sullivan's Island and Wild Dunes on the other end, the Isle of Palms offers a beach atmosphere on the ocean side of the island, and excellent creek and river access on the other. Combined with a laid back lifestyle, the Isle of Palms is perfect for vacationing families each year looking to have some fun in the sun. In fact, many of these visitors tend to stay because they like it so much. These are all of the single family homes for sale on the Isle of Palms, SC 29451.
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54 Photos
3002 Waterway Boulevard
Isle of Palms, SC 29451
Residential
MLS# 25017180 / Active
4 br, 3 ba, 2262 Sqft
Welcome to 3002 Waterway Blvd - a fabulous 4-bedroom, 3-bath home situated on a spacious 0.38-acre lot in the heart of the Isle of Palms. This beau...
$1,850,000
Provided courtesy of Carolina One Real Estate
63 Photos
14 55th Avenue
Isle of Palms, SC 29451
Isle Of Palms
Residential
MLS# 25017111 / Active
5 br, 5 ba, 1 Half Bath, 4030 Sqft
Welcome to 14 55th Avenue--2nd row newly built custom home just steps away from the beach. Located in the highly sought after section of IOP where ...
$3,950,000
Provided courtesy of 32 South Properties, LLC
48 Photos
109 Carolina Boulevard
Isle of Palms, SC 29451
Isle Of Palms
Residential
MLS# 25016852 / Active
6 br, 5 ba, 3394 Sqft
Excellent opportunity to own a great renovated beach house on the south end of IOP with a high stream of annual revenue! The house and grounds have...
$2,452,000
Provided courtesy of East Islands Real Estate
13 Photos
101 Palm Boulevard UNIT B3
Isle of Palms, SC 29451
Residential
MLS# 25016792 / Active
n/a br, n/a ba, 144 Sqft
Jet Dock designed for 18' boat up to 2,000 lbs. Perfectly situated between Sullivan's Island and the Isle of Palms, the Two Island Marina is locate...
$150,000
Provided courtesy of Carroll Realty
12 Photos
101 Palm Boulevard UNIT A7
Isle of Palms, SC 29451
Residential
MLS# 25016791 / Active
n/a br, n/a ba, 1500 Sqft
RARE 100' of dockage available with potential to add another 50' contiguous dock space. 50A electrical service and water available in two pedestals...
$600,000
Provided courtesy of Carroll Realty
12 Photos
101 Palm Boulevard UNIT B12
Isle of Palms, SC 29451
Residential
MLS# 25016789 / Active
n/a br, n/a ba, 780 Sqft
Step aboard and set sail! Approx. 52' in-water boat slip perfectly situated between Sullivan's Island and the Isle of Palms. Two Island Marina is l...
$325,000
Provided courtesy of Carroll Realty
30 Photos
1400 Ocean Boulevard UNIT 106b
Isle of Palms, SC 29451
Oceanside
Residential
MLS# 25016779 / Active
2 br, 2 ba, 960 Sqft
This 2 bedroom, 2 bath condo is across the street from the beach and has a private balcony overlooking the pool. The kitchen, dining & living areas...
$650,000
Provided courtesy of Brand Name Real Estate
32 Photos
108 Carolina Boulevard
Isle of Palms, SC 29451
Isle Of Palms
Residential
MLS# 25016709 / Active
5 br, 4 ba, 2 Half Bath, 4415 Sqft
New co-ownership opportunity: Own one-eighth of this professionally managed, turnkey home. Located on the quiet side of the island, this beautifull...
$589,000
Reduced -$10,000
Reduced -$10,000
Provided courtesy of Smith Spencer Real Estate
30 Photos
108 Carolina Boulevard
Isle of Palms, SC 29451
Isle Of Palms
Residential
MLS# 25016476 / Active
5 br, 4 ba, 2 Half Bath, 4415 Sqft
New co-ownership opportunity: Own one-eighth of this professionally managed, turnkey home. Located on the quiet side of the island, this beautifull...
$559,000
Reduced -$40,000
Reduced -$40,000
Provided courtesy of Smith Spencer Real Estate
60 Photos
2619 Buccaneer Road
Isle of Palms, SC 29451
Goat Island
Residential
MLS# 25015528 / Active
4 br, 3 ba, 1743 Sqft
Escape to Goat Island in this upgraded 4BR/3BA deepwater retreat--accessible only by boat and offering rare privacy with vacant lots on both sides....
$1,300,000
Provided courtesy of Coldwell Banker Realty
75 Photos
3 Cross Lane
Isle of Palms, SC 29451
Forest Trail
Residential
MLS# 25014752 / Active
4 br, 3 ba, 2 Half Bath, 5074 Sqft
Now offered at $355,000 less!! Unbeatable value on Isle of Palms for this level of square footage, views, and lifestyle amenities! Experience timel...
$3,495,000
Provided courtesy of The Boulevard Company
75 Photos
4001 Palm Boulevard
Isle of Palms, SC 29451
Isle Of Palms
Residential
MLS# 25014624 / Active
6 br, 6 ba, 1 Half Bath, 5005 Sqft
MOTIVATED SELLERS. PRICED TO SELL! Welcome to 4001 Palm Blvd, an iconic second-row coastal sanctuary on Isle of Palms offering breathtaking ocean v...
$5,595,000
Provided courtesy of The Boulevard Company
20 Photos
814 Palm Boulevard
Isle of Palms, SC 29451
Isle Of Palms
Residential
MLS# 25014287 / Active
5 br, 5 ba, 1 Half Bath, 3200 Sqft
Beautiful 5 Bedroom, 5.5 Bathroom 3,200 square foot new construction home scheduled for completion in late July with $250k in annual income potenti...
$3,495,000
Provided courtesy of The Boulevard Company
69 Photos
905 Palm Boulevard
Isle of Palms, SC 29451
Isle Of Palms
Residential
MLS# 25013993 / Active
3 br, 3 ba, 1 Half Bath, 4275 Sqft
Settle into the gentle rhythms of Lowcountry waterfront living in this modern masterpiece on Isle of Palms. Every detail of this magnificent proper...
$8,000,000
Provided courtesy of William Means Real Estate, LLC
41 Photos
3307 Waterway Boulevard
Isle of Palms, SC 29451
Isle Of Palms
Residential
MLS# 25013915 / Active
5 br, 5 ba, 2 Half Bath, 4234 Sqft
**ALL PHOTOS ARE RENDERINGS. HOME TO BE COMPLETED END OF SEPTEMBER 2025. HOME HAS BEEN COMPLETELY GUTTED, REDESIGNED, AND BEING COMPLETELY REMODELE...
$4,699,000
Provided courtesy of The Boulevard Company
23 Photos
601 Ocean Boulevard
Isle of Palms, SC 29451
Residential
MLS# 25013787 / Active
5 br, 5 ba, 1 Half Bath, 3624 Sqft
Beautiful 2nd row home located in the most desirable location on IOP (South IOP) directly across the street from the 6th Ave. beach path! The prope...
$5,285,000
Provided courtesy of Salmonsen Realty
38 Photos
13 32nd Avenue
Isle of Palms, SC 29451
Residential
MLS# 25013508 / Active
3 br, 2 ba, 1981 Sqft
Welcome to 13 32nd Avenue--a beautifully updated, turn-key island retreat priced below its recent $1.87M appraisal (available upon request). Just t...
$1,795,000
Reduced -$55,000
Reduced -$55,000
Provided courtesy of Keller Williams Realty Charleston
47 Photos
11 Tabby Lane
Isle of Palms, SC 29451
Residential
MLS# 25012193 / Active
6 br, 6 ba, 1 Half Bath, 6159 Sqft
Welcome to a rare opportunity to own an architectural masterpiece by esteemed designer Carl McCants and renowned custom builder Fox Creek Homes. Lo...
$11,500,000
Provided courtesy of Carolina One Real Estate
67 Photos
124 Charleston Boulevard
Isle of Palms, SC 29451
Residential
MLS# 25012155 / Active
5 br, 5 ba, 1 Half Bath, 4957 Sqft
Highly anticipated and undeniably worth it--you've been patiently waiting for a home like this, and it's finally here. This is the one! Ideally sit...
$6,745,000
Provided courtesy of The Boulevard Company
45 Photos
1140 Ocean Boulevard UNIT #201
Isle of Palms, SC 29451
Ocean Boulevard
Residential
MLS# 25012049 / Active
4 br, 3 ba, 1975 Sqft
Experience the ultimate in coastal luxury with this Furnished OCEAN FRONT condo. Laid-back island living meets refined sophistication in this expan...
$2,500,000
Provided courtesy of Keller Williams Charleston Islands
67 Photos
625 Ocean Boulevard
Isle of Palms, SC 29451
Residential
MLS# 25011924 / Active
4 br, 3 ba, 1 Half Bath, 3611 Sqft
Once in a lifetime opportunity to own this wonderful 2nd row, ocean view home that has been in the same family for almost 50 years! You will love t...
$3,125,000
Reduced -$75,000
Reduced -$75,000
Provided courtesy of Carolina One Real Estate
The data relating to real estate for sale on this web site comes in part from the Broker ReciprocitySM Program of the Charleston Trident Multiple Listing Service. Real estate listings held by brokerage firms other than EXP Realty LLC are marked with the Broker ReciprocitySM logo or the Broker ReciprocitySM thumbnail logo (a little black house) and detailed information about them includes the name of the listing brokers. Last updated on 06-24-2025 8:29 AM EST .
The broker providing these data believes them to be correct, but advises interested parties to confirm them before relying on them in a purchase decision.
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