Most of the waterfront homes are offered on the Leeds Avenue side of North Charleston along the banks of the Ashley River, yet some can also be found on the Park Circle side near the Old North Charleston. 
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7 Photos 7221 Investment Drive North Charleston, SC 29418

7221 Investment Drive
North Charleston, SC 29418
Commercial Sales

MLS# 31007800 / Active

7221 Investment Drive is a +/-18,471 SF Class A flex laboratory facility situated on +/-1.70 acres in North Charleston`s established industrial cor... 

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$5,500,000
Provided courtesy of
4 Photos 7263 Cross Park Drive North Charleston, SC 29418

7263 Cross Park Drive
North Charleston, SC 29418
Commercial Sales

MLS# 31007795 / Active

Located on Cross Park Drive within the Palmetto Commercial Center, this+/-0.57-acre lot offers convenient access to I-26 and Charleston Internation... 

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$500,000
Provided courtesy of NAI Charleston, LLC
1 Photos 4200 Piggly Wiggly Drive North Charleston, SC 29405

4200 Piggly Wiggly Drive
North Charleston, SC 29405
Commercial Lease

MLS# 31007790 / Active
3.00 Acres, Zoning: n/a
Municipality: n/a
$66000.00 Annual PSF

3 Acre truck yard located at the end of Piggly Wiggly Drive. Zoned M1 Light Industrial in the City of N. Charleston. Ready for occupancy. Centrally... 

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$66,000
Provided courtesy of
10 Photos 4330 Cheyenne Street UNIT Building 2 North Charleston, SC 29405

4330 Cheyenne Street UNIT Building 2
North Charleston, SC 29405
Commercial Lease

MLS# 31007782 / Active
0.00 Acres, Zoning: n/a
Municipality: n/a
$41180.00 Annual PSF

Exceptional sublease opportunity for 2,840 SF of turnkey flex space, featuring a full interior upfit completed in January2026. This well-maintained... 

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$41,180
Provided courtesy of NAI Charleston, LLC
10 Photos 4662 Rivers Avenue North Charleston, SC 29405

4662 Rivers Avenue
North Charleston, SC 29405
Commercial Lease

MLS# 31007778 / Active
0.00 Acres, Zoning: n/a
Municipality: n/a
$20.00 Annual PSF

Spacious Flex Space zoned B-2 this building offers a wide-open layout perfect for a variety of uses such as retail, office, showroom space, worksho... 

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$20
Provided courtesy of
9 Photos 3844 Leeds Avenue North Charleston, SC 29405

3844 Leeds Avenue
North Charleston, SC 29405
Commercial Lease

MLS# 31007772 / Active
0.00 Acres, Zoning: n/a
Municipality: n/a
$21011.00 Annual PSF

Formally a law office ,this location is situated beside Charleston County`sGovernment Building and the Charleston DMV.Excellent visibility from Lee... 

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$21,011
Provided courtesy of
1 Photos 8250 Patriot Blvd Boulevard UNIT Building 3 North Charleston, SC 29418

8250 Patriot Blvd Boulevard UNIT Building 3
North Charleston, SC 29418
Commercial Lease

MLS# 31007771 / Active
0.00 Acres, Zoning: n/a
Municipality: n/a
n/a Annual PSF

Superior infill location with direct access to Palmetto Commerce Park+/-180,099 SF across two buildings, divisible down to +/-16,000 SFExcellent ac... 

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$0
Provided courtesy of Bridge Corporate Solutions, LLC
13 Photos 7421 W Spartan Boulevard North Charleston, SC 29418

7421 W Spartan Boulevard
North Charleston, SC 29418
Commercial Lease

MLS# 31007767 / Active
0.00 Acres, Zoning: n/a
Municipality: n/a
$12.00 Annual PSF

Well located freestanding metal office/warehouse building, equipped with two oversized drive in doors and two position loading dock well, approxima... 

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$12
Provided courtesy of
11 Photos 3605 Meeting Street Road North Charleston, SC 29405

3605 Meeting Street Road
North Charleston, SC 29405
Commercial Sales

MLS# 31007739 / Active

3605 Meeting Street Road offers a rare owner-user or investor opportunity in North Charleston`s established Meeting Street Road corridor. The prope... 

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$1,250,000
Provided courtesy of Dunes Commercial Properties
17 Photos 10587 Hwy 78 Summerville, SC 29483

10587 Hwy 78
Summerville, SC 29483
Commercial Lease

MLS# 31007735 / Active
1.79 Acres, Zoning: n/a
Municipality: n/a
$8700000.00 Annual PSF

Newly renovated standalone office building available for lease or salein a beautiful and convenient setting. The property is zonedCC - Community Co... 

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$8,700,000
Provided courtesy of
18 Photos 10587 Hwy 78 Summerville, SC 29483

10587 Hwy 78
Summerville, SC 29483
Commercial Sales

MLS# 31007734 / Active

Newly renovated standalone office building available for salein a beautiful and convenient setting. The property is zonedCC - Community Commercial ... 

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$1,295,000
Provided courtesy of
2 Photos 4425 Belle Oak Dr Drive North Charleston, SC 29405

4425 Belle Oak Dr Drive
North Charleston, SC 29405
Commercial Lease

MLS# 31007720 / Active
0.00 Acres, Zoning: n/a
Municipality: n/a
$26.00 Annual PSF

+/-6,793 SF freestanding commercial buildingSituated on a spacious +/-1.81-acre parcelAvailable For Sale or LeaseAmple on-site parking with room fo... 

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$26
Provided courtesy of Bridge Corporate Solutions, LLC
11 Photos 7400 Northside Drive North Charleston, SC 29420

7400 Northside Drive
North Charleston, SC 29420
Commercial Lease

MLS# 31007711 / Active
0.00 Acres, Zoning: n/a
Municipality: n/a
$186320.00 Annual PSF

Former Ruby Tuesday on Ashley Phosphate Rd. TIA and delivery available for credit tenants. Will consider a ground lease as well. Inquire for additi... 

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$186,320
Provided courtesy of Charleston Commercial
5 Photos 7381 E Spartan Boulevard North Charleston, SC 29418

7381 E Spartan Boulevard
North Charleston, SC 29418
Commercial Lease

MLS# 31007710 / Active
0.00 Acres, Zoning: n/a
Municipality: n/a
$7.00 Annual PSF

This is a 32,000 square foot warehouse/distribution facility off of Ashley Phosphate Road on East Spartan Boulevard. 31,620 SF Warehouse and 380 SF... 

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$7
Provided courtesy of
7 Photos 3901 Rivers Avenue North Charleston, SC 29405

3901 Rivers Avenue
North Charleston, SC 29405
Commercial Lease

MLS# 31007695 / Active
0.00 Acres, Zoning: n/a
Municipality: n/a
$18.00 Annual PSF

3901 Rivers Avenue is a 2,100 square foot freestanding building positioned off well traveled Rivers Avenue in North Charleston. This property has e... 

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$18
Provided courtesy of Belk / Lucy
1 Photos 4254 Spruill Avenue North Charleston, SC 29405

4254 Spruill Avenue
North Charleston, SC 29405
Commercial Sales

MLS# 31007691 / Active

Premier Spruill Avenue Frontage For Sale - $3,880,000. Primary Gateway to Park Circle. 4254, -56, -58 Spruill Avenue. Includes TMS 4701600074, -075... 

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$3,880,000
Provided courtesy of
3 Photos 2015 Cosgrove Ave Avenue UNIT B North Charleston, SC 29405

2015 Cosgrove Ave Avenue UNIT B
North Charleston, SC 29405
Commercial Lease

MLS# 31007682 / Active
0.00 Acres, Zoning: n/a
Municipality: n/a
$30.00 Annual PSF

The available space is a rear shell unit, offering a blank canvas for the right tenant. The landlord is seeking a tenant to customize and lease the... 

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$30
Provided courtesy of
6 Photos 4030 Ashley Phosphate Road North Charleston, SC 29418

4030 Ashley Phosphate Road
North Charleston, SC 29418
Commercial Lease

MLS# 31007678 / Active
0.00 Acres, Zoning: n/a
Municipality: n/a
$16.00 Annual PSF

Three Units Available immediately for lease - 1,900-3,800 SF 

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$16
Provided courtesy of
4 Photos 7195 Cross County Road UNIT Building 2 North Charleston, SC 29418

7195 Cross County Road UNIT Building 2
North Charleston, SC 29418
Commercial Lease

MLS# 31007676 / Active
4.70 Acres, Zoning: n/a
Municipality: n/a
$15.00 Annual PSF

Located at 7195 Cross County Road in North Charleston, this flex warehouse project within the Cross County Commerce Park offers modern, functional ... 

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$15
Provided courtesy of GCB Real Estate and Investments
4 Photos 7195 Cross County Road UNIT Building 1 North Charleston, SC 29418

7195 Cross County Road UNIT Building 1
North Charleston, SC 29418
Commercial Lease

MLS# 31007675 / Active
4.70 Acres, Zoning: n/a
Municipality: n/a
$15.00 Annual PSF

Located at 7195 Cross County Road in North Charleston, this flex warehouse project within the Cross County Commerce Park offers modern, functional ... 

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$15
Provided courtesy of GCB Real Estate and Investments
3 Photos 1634 Sumner Avenue North Charleston, SC 29406

1634 Sumner Avenue
North Charleston, SC 29406
Commercial Sales

MLS# 31007673 / Active

R-2 Multifamily Development Opportunity - Corner Lot Near Park Circle Recently zoned R-2 Multifamily by the City of N. Chas, this 0.8-acre corner l... 

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$800,000
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Broker Reciprocity The data relating to real estate for sale on this web site comes in part from the Broker ReciprocitySM Program of the Charleston Trident Multiple Listing Service. Real estate listings held by brokerage firms other than EXP Realty LLC are marked with the Broker ReciprocitySM logo or the Broker ReciprocitySM thumbnail logo (a little black house) and detailed information about them includes the name of the listing brokers. Last updated on 07-06-2026 11:52 PM EST . The broker providing these data believes them to be correct, but advises interested parties to confirm them before relying on them in a purchase decision. Copyright 2026 Charleston Trident Multiple Listing Service, Inc. All rights reserved.
Commercial Sale/Lease: Copyright 2026 South Carolina commercial MLS, Inc. All rights reserved. Last updated on 07-06-2026 11:52 PM EST est.

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